Antigen assay with the potential to aid in diagnosis of blastomycosis

被引：134

作者：

Durkin, M ^{[1
]}

Witt, J ^{[1
]}

LeMonte, A ^{[1
]}

Wheat, B ^{[1
]}

Connolly, P ^{[1
]}

机构：

[1] MiraVista Diagnost Mira Bella Technol, Indianapolis, IN 46241 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2004年 / 42卷 / 10期

关键词：

D O I：

10.1128/JCM.42.10.4873-4875.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report results of an immunoassay for Blastomyces dermatitidis antigenuria. Sensitivity was 92.9%, and specificity was 79.3%. Cross-reactions occurred in 96.3% of patients with histoplasmosis, 100% of patients with paracoccidioidomycosis, 70% of patients with penicilliosis marneffei, 2.9% of patients with cryptococcosis, and 1.1% of patients with aspergillosis. Reproducibility was 96.3%. These findings support a potential role for antigen testing in blastomycosis.

引用

页码：4873 / 4875

页数：3

共 13 条

[1] STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].

BLAND, JM ;

ALTMAN, DG .

LANCET, 1986, 1 (8476) :307-310

[2] Blastomycosis [J].

Bradsher, RW ;

Chapman, SW ;

Pappas, PG .

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2003, 17 (01) :21-+

[3]

Chapman S W, 1997, Semin Respir Infect, V12, P219

[4] Comparison of radioimmunoassay and enzyme-linked immunoassay methods for detection of Histoplasma capsulatum var. capsulatum antigen [J].

Durkin, MM ;

Connolly, PA ;

Wheat, LJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (09) :2252-2255

[5] Immunological and chemical characterization of glycoproteins in IEF fractions of Blastomyces dermatitidis yeast lysate antigen [J].

Fisher, MA ;

Legendre, AM ;

Scalarone, GM .

MYCOSES, 1997, 40 (3-4) :83-90

[6] LABORATORY METHODS FOR THE DIAGNOSIS AND CONFIRMATION OF SYSTEMIC MYCOSES [J].

KAUFMAN, L .

CLINICAL INFECTIOUS DISEASES, 1992, 14 :S23-S29

[7]

Lemos L B, 2000, Ann Diagn Pathol, V4, P391, DOI 10.1053/adpa.2000.20755

[8]

Lemos Luciano B, 2002, Ann Diagn Pathol, V6, P194, DOI 10.1053/adpa.2002.34575

[9] Itraconazole prophylaxis for fungal infections in patients with advanced human immunodeficiency virus infection: Randomized, placebo-controlled, double-blind study [J].

McKinsey, DS ;

Wheat, LJ ;

Cloud, GA ;

Pierce, M ;

Black, JR ;

Bamberger, DM ;

Goldman, M ;

Thomas, CJ ;

Gutsch, HM ;

Moskovitz, B ;

Dismukes, WE ;

Kauffman, CA .

CLINICAL INFECTIOUS DISEASES, 1999, 28 (05) :1049-1056

[10] Blastomycosis in northeast Tennessee [J].

Vasquez, JE ;

Mehta, JB ;

Agrawal, R ;

Sarubbi, FA .

CHEST, 1998, 114 (02) :436-443

← 1 2 →