Selective deprotection of acetals with Me3SiCH2MgCl.: Peterson-type olefination of acetals

被引:5
作者
Chiang, CC [1 ]
Chen, YH [1 ]
Hsieh, YT [1 ]
Luh, TY [1 ]
机构
[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
关键词
D O I
10.1021/jo000317h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
By employing the chelation strategy, treatment of an acetal of a contiguous diol with Me3SiCH2MgCl liberates the corresponding diol regioselectively. In addition, acetals of different structural variety are transformed upon treatment with Me2SiCH2MgCl and ZnI2 into the corresponding olefination products in good yield.
引用
收藏
页码:4694 / 4697
页数:4
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