1-(1,2,3-triazol-4-yl)-benzimidazolones, a new series of heterocyclic derivatives

被引:10
作者
Bertelli, L
Biagi, G
Calderone, V
Giorgi, I
Livi, O [1 ]
Scartoni, V
Barili, PL
机构
[1] Univ Pisa, Dipartimento Sci Farmaceut, I-56126 Pisa, Italy
[2] Univ Pisa, Dipartimento Chim Bioorgan & Biofarm, I-56126 Pisa, Italy
关键词
D O I
10.1002/jhet.5570370525
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
New 1-(1,2,3-triazol-4-yl)-benzimidazolone derivatives were obtained on pursuing research about new tricyclic derivatives of medicinal interest, bearing a 1,2,3-triazole ring fused with another heterocyclic ring. 1-[(5-Carboxamido)-1,2,3-triazol-4-yl] was prepared by four different chemical routes and it was unequivocally confirmed by spectroscopic methods. Its chemical behaviour, was evaluated by some common chemical reactions such as hydrolysis, esterification, decarboxylation, nitration and N-methylation.
引用
收藏
页码:1169 / 1176
页数:8
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