Synthesis and ESR studies of nitronyl nitroxide-tethered oligodeoxynucleotides

被引：28

作者：

Okamoto, A ^{[1
]}

Inasaki, T

Saito, I

机构：

[1] Kyoto Univ, Fac Engn, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan

[2] Nihon Univ, Sch Engn, NEWCAT Inst, Koriyama, Fukushima 9638642, Japan

[3] Japan Sci & Technol Corp, SORST, Koriyama, Fukushima 9638642, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 05期

关键词：

pyrene; oligodeoxynucleotide; fluorescence; quadruplex;

D O I：

10.1016/j.tetlet.2004.12.012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report oil the development of a nucleoside labeled with a nitronyl nitroxide group, U-NN, and the synthesis of oligodeoxynucleotides containing U-NN. The spin signals of U-NN. containing oligodeoxynucleotides varied with the degree of hybridization of the complementary strand and the distance between nitronyl nitroxide spins. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：791 / 795

页数：5

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