Emergency endovascular stent-grafting for life-threatening acute type B aortic dissections

被引:63
作者
Duebener, LF
Lorenzen, P
Richardt, G
Misfeld, M
Nötzold, A
Hartmann, F
Sievers, HH
Geist, V
机构
[1] Univ Hosp Schleswig Holstein, Dept Cardiac Surg, D-23538 Lubeck, Germany
[2] Univ Hosp Schleswig Holstein, Dept Cardiol, D-23538 Lubeck, Germany
[3] Heart Ctr Bad Segeberg, Dept Cardiol, Bad Segeberg, Germany
关键词
D O I
10.1016/j.athoracsur.2004.03.107
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. There is still a considerable controversy regarding optimal treatment for patients with acute type B aortic dissection. Patients with complicated disease are particularly challenging. for cardiovascular treatment. Early surgery for acute dissections of the descending aorta with life-threatening complications is known to carry a high mortality. Endovascular stent grafting is developing as an alternative treatment mainly for chronic stages of type B aortic dissection. It is not clear whether endovascular stent grafting is safe and effective in emergency treatment of acute type B aortic dissection. Methods. In 10 patients (7 men, 3 women; mean age, 59.2 years; range, 46 to 65 years), enclovascular stent grafting was performed within 11.0 +/- 5.9 hours (range, 4 to 24 hours) of diagnosis of complications. Indications for acute intervention included contained rupture, hematothorax, life-threatening malperfusion, and refractory pain. Using a retrograde endovascular route after surgical exposure of the femoral artery, self-expanding stent prostheses consisting of polyester-covered Nitinol (Talent, World Medical; mean diameter, 40 +/- 4 mm; length, 10 cm) were placed into the descending aorta distal to the subclavian artery. Before discharge and on follow-up visits, imaging of the aorta was performed using computed tomography. Results. In 9 of 10 patients (90%), the primary entry could be completely occluded with the endovascular stent. Early mortality was 20% (2 of 10): 1 patient died after disruption of the intimal layer distal to the stent, and 1 patient died in hemorrhagic shock after surgical fenestration of the abdominal aorta for persistent malperfusion. Three patients (30%) required consecutive surgical treatment: indications included acute development of retrograde type A aortic dissection, acute stent dislocation by fractured wires and secondary leakage, and late formation of an aneurysm of the descending aorta 6 months after endovascular stent grafting. There were no surgical or late deaths. Conclusions. Our experience provides some evidence that early mortality of life-threatening acute type B aortic dissection may be reduced by emergency endovascular stent grafting and that this form of treatment is a promising therapeutic option. Refinements, especially in stent design and application, may further improve the prognosis of patients in the life-threatening situation of complicated acute type B aortic dissection. (C) 2004 by The Society of Thoracic Surgeons.
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页码:1261 / 1267
页数:7
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