The inner gel component of Aloe Vera suppresses bacterial-induced pro inflammatory cytokines from human immune cells

被引：56

作者：

Habeeb, Fatema

Stables, Graham

Bradbury, Fiona

Nong, Stephanie

Cameron, Pamela

Plevin, Robin

Ferro, Valerie A.

机构：

[1] Kuwait Univ, Fac Allied Hlth, Med Lab Sci, Sualibikhat 90805, Kuwait

[2] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow G4 0NR, Lanark, Scotland

来源：

METHODS | 2007年 / 42卷 / 04期

关键词：

aloe vera; anti-inflammatory; inflammation; pro-inflammatory cytokines;

D O I：

10.1016/j.ymeth.2007.03.005

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-alpha and IL-1 beta, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated. (C) 2007 Published by Elsevier Inc.

引用

收藏

页码：388 / 393

页数：6

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