A hypothesis that explains the heterogeneity of drug-induced immune thrombocytopenia

被引:4
作者
Li, Renhao [1 ]
机构
[1] Univ Texas Hlth Sci Ctr Houston, Dept Biochem & Mol Biol, Ctr Membrane Biol, Houston, TX 77030 USA
关键词
QUININE-DEPENDENT ANTIBODIES; GLYCOPROTEIN IX; DOMAIN; BINDING; SITE;
D O I
10.1182/blood-2009-09-242297
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:914 / 914
页数:1
相关论文
共 10 条
[1]   Drug-induced thrombocytopenia: localization of the binding site of GPIX-specific quinine-dependent antibodies [J].
Asvadi, P ;
Ahmadi, Z ;
Chong, BH .
BLOOD, 2003, 102 (05) :1670-1677
[2]   Patients with quinine-induced immune thrombocytopenia have both "drug-dependent" and "drug-specific" antibodies [J].
Bougie, Daniel W. ;
Wilker, Peter R. ;
Aster, Richard H. .
BLOOD, 2006, 108 (03) :922-927
[3]   Rifampicin-dependent antibodies bind a similar or identical epitope to glycoprotein IX-specific quinine-dependent antibodies [J].
Burgess, JK ;
Lopez, JA ;
Gaudry, LE ;
Chong, BH .
BLOOD, 2000, 95 (06) :1988-1992
[4]  
DILL KA, 1991, ANNU REV BIOCHEM, V60, P795, DOI 10.1146/annurev.biochem.60.1.795
[5]   An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies [J].
Gentilini, G ;
Curtis, BR ;
Aster, RH .
BLOOD, 1998, 92 (07) :2359-2365
[6]   Quinine-induced immune thrombocytopenic purpura followed by hemolytic uremic syndrome [J].
Glynne, P ;
Salama, A ;
Chaudhry, A ;
Swirsky, D ;
Lightstone, L .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1999, 33 (01) :133-137
[7]   Binding of platelet glycoprotein Ibβ through the convex surface of leucine-rich repeats domain of glycoprotein IX [J].
Mo, X. ;
Nguyen, N. X. ;
McEwan, P. A. ;
Zheng, X. ;
Lopez, J. A. ;
Emsley, J. ;
Li, R. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 (09) :1533-1540
[8]   Fine specificity of drug-dependent antibodies reactive with a restricted domain of platelet GPIIIA [J].
Peterson, Julie A. ;
Nelson, Tamara N. ;
Kanack, Adam J. ;
Aster, Richard H. .
BLOOD, 2008, 111 (03) :1234-1239
[9]   A novel adaptation of the integrin PSI domain revealed from its crystal structure [J].
Xiong, JP ;
Stehle, T ;
Goodman, SL ;
Arnaout, MA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (39) :40252-40254
[10]   Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces [J].
Zhu, Jianghai ;
Luo, Bing-Hao ;
Xiao, Tsan ;
Zhang, Chengzhong ;
Nishida, Noritaka ;
Springer, Timothy A. .
MOLECULAR CELL, 2008, 32 (06) :849-861