The synchronization of superparamagnetic beads driven by a micro-magnetic ratchet

被引：36

作者：

Gao, Lu ^{[1
]}

Gottron, Norman J., III ^{[1
]}

Virgin, Lawrence N. ^{[1
]}

Yellen, Benjamin B. ^{[1
]}

机构：

[1] Duke Univ, Dept Mech Engn & Mat Sci, CBIMMS, Durham, NC 27708 USA

来源：

LAB ON A CHIP | 2010年 / 10卷 / 16期

关键词：

D O I：

10.1039/c003836a

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present theoretical, numerical, and experimental analyses on the non-linear dynamic behavior of superparamagnetic beads exposed to a periodic array of micro-magnets and an external rotating field. The agreement between theoretical and experimental results revealed that non-linear magnetic forcing dynamics are responsible for transitions between phase-locked orbits, sub-harmonic orbits, and closed orbits, representing different mobility regimes of colloidal beads. These results suggest that the non-linear behavior can be exploited to construct a novel colloidal separation device that can achieve effectively infinite separation resolution for different types of beads, by exploiting minor differences in their bead's properties. We also identify a unique set of initial conditions, which we denote the "devil's gate'' which can be used to expeditiously identify the full range of mobility for a given bead type.

引用

页码：2108 / 2114

页数：7

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