Use of electroconductive biomaterials for engineering tissues by 3D printing and 3D bioprinting

被引:25
作者
Alizadeh, Parvin [1 ,2 ]
Soltani, Mohammad [2 ]
Tutar, Rumeysa [1 ,3 ]
Apu, Ehsanul Hoque [4 ,5 ]
Maduka, Chima V. [5 ,6 ,7 ]
Unluturk, Bige Deniz [4 ,5 ]
Contag, Christopher H. [4 ,5 ,7 ]
Ashammakhi, Nureddin [1 ,4 ,5 ]
机构
[1] Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
[2] Tarbiat Modares Univ, Fac Engn & Technol, Dept Mat Sci & Engn, POB 14115-143, Tehran, Iran
[3] Istanbul Univ Cerrahpasa Avclar, Fac Engn, Dept Chem, TR-34320 Istanbul, Turkey
[4] Michigan State Univ, Inst Quantitat Hlth Sci & Engn IQ, E Lansing, MI 48824 USA
[5] Michigan State Univ, Dept Biomed Engn BME, E Lansing, MI 48824 USA
[6] Michigan State Univ, Coll Vet Med, Comparat Med & Integrat Biol, E Lansing, MI 48824 USA
[7] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA
来源
3D BIOPRINTING | 2021年 / 65卷 / 03期
基金
美国国家卫生研究院;
关键词
CONDUCTIVE INJECTABLE HYDROGELS; STEM-CELL DIFFERENTIATION; ELECTRICAL-STIMULATION; CARBON NANOTUBES; NANOFIBROUS SCAFFOLDS; HYBRID HYDROGELS; IN-VITRO; POLYPYRROLE; GRAPHENE; ANTIBACTERIAL;
D O I
10.1042/EBC20210003
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
Existing methods of engineering alternatives to restore or replace damaged or lost tissues are not satisfactory due to the lack of suitable constructs that can fit precisely, function properly and integrate into host tissues. Recently, three-dimensional (3D) bioprinting approaches have been developed to enable the fabrication of pre-programmed synthetic tissue constructs that have precise geometries and controlled cellular composition and spatial distribution. New bioinks with electroconductive properties have the potential to influence cellular fates and function for directed healing of different tissue types including bone, heart and nervous tissue with the possibility of improved outcomes. In the present paper, we review the use of electroconductive biomaterials for the engineering of tissues via 3D printing and 3D bioprinting. Despite significant advances, there remain challenges to effective tissue replacement and we address these challenges and describe new approaches to advanced tissue engineering.
引用
收藏
页码:441 / 466
页数:26
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