2,6-diaroyl-3,5-diaryl-4-methyltetrahydro-1,4-thiazine-1,1-dioxides - A synthetic and stereochemical study

被引:9
作者
Gnanadeepam, M
Selvaraj, S [1 ]
Perumal, S
Hewlins, MJE
Lycka, A
机构
[1] Madurai Kamaraj Univ, Sch Chem, Madurai 625021, Tamil Nadu, India
[2] Fatima Coll, Dept Chem, Madurai 625018, Tamil Nadu, India
[3] Univ Wales, Dept Chem, Cardiff CF1 3TB, S Glam, Wales
[4] Res Inst Organ Synth, CS-53218 Pardubice, Czech Republic
关键词
2,6-diaroyl-3,5-diaryl-4-methyltetrahydro-1,4-thiazine-1,1-dioxides; 2,2'-sulfonylbis(1,3-diarylprop-2-en-1-ones); methylamine; bis(aroylmethyl)sulfones; NMR spectra; stereochemistry;
D O I
10.1080/10426509908044980
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Conjugate addition of methylamine over 2,2'-sulfonylbis(1,3-diarylprop-2-en-1-ones) in dimethylformamide gave the hitherto unknown 2,6-diaroyl-3,5-diaryl-4-methyltetrahydro-1,4-thiazine-1,1-dioxides in very good yields. The same thiazines were also obtained by condensation of bis(aroylmethyl)sulfones with aromatic aldehydes and methylamine. The structure and stereochemistry of the compounds were deduced from elemental analysis and spectral data.
引用
收藏
页码:167 / 173
页数:7
相关论文
共 4 条
[1]  
BOULTON AJ, 1984, COMPREHENSIVE HETERO, P1038
[2]  
GNANADEEPAM M, COMMUNICATION
[3]  
SELVARAJ S, 1994, INDIAN J CHEM B, V33, P67
[4]  
SELVARAJ S, UNPUB