Direct oxidative amidation of aldoses by iodine in ammonia water

被引：9

作者：

Chen, MY

Hsu, JL

Shie, JJ

Fang, JM ^{[1
]}

机构：

[1] Taipei Nursing Coll, Dept Gen Educ, Taipei, Taiwan

[2] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2003年 / 50卷 / 01期

关键词：

aldoses; amides; iodine; ammonia;

D O I：

10.1002/jccs.200300018

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Aldopentoses, aldohexoses and the benzylated derivatives reacted with iodine in ammonia water at room temperature to give their corresponding saccharide amides in high yields. The reactions proceeded with oxidation of the aldose hemiacetals by iodine to generate the saccharide lactone intermediates, which underwent ammonolysis in situ to give the saccharide amides.

引用

收藏

页码：129 / 133

页数：5

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