Case Report: Dexatrim (Phenylpropanolamine) as a cause of myocardial infarction

被引：15

作者：

Pilsczek, FH

Karcic, AA

Freeman, I

机构：

[1] Beth Israel Deaconess Med Ctr, Div Infect Dis, Boston, MA 02215 USA

[2] Lahey Clin Fdn, Div Electrophysiol, Burlington, MA USA

[3] Nassau Univ, Med Ctr, Div Cardiovasc Dis, E Meadow, NY USA

来源：

HEART & LUNG | 2003年 / 32卷 / 02期

关键词：

D O I：

10.1067/mhl.2003.27

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Phenylpropanolamine (PPA) is a sympathetic amine used in over-the-counter cold remedies and weight-control preparations worldwide. Its use has been associated with hypertensive episodes and hemorrhagic strokes in younger women. Several reports have linked the abuse of PPA with myocardial injury, especially when overdose is involved. We report here the first case of Dexatrim (PPA)-induced myocardial injury in a young woman who was using it at recommended doses for weight control. In addition, we review the 7 other cases of PPA related myocardial injury that have been reported so far. Physicians and patients should be alert to the potential cardiac risk associated with the use of PPA, even at doses generally considered to be safe.

引用

页码：100 / 104

页数：5

共 20 条

[1]

[Anonymous], 2002, COMPLETE DRUG REFERE

[2]

CHOUINARD G, 1978, CAN MED ASSOC J, V119, P729

[3] IMPAIRMENT OF ENDOTHELIUM-DEPENDENT PULMONARY-ARTERY RELAXATION IN CHRONIC OBSTRUCTIVE LUNG-DISEASE [J].