Severe cardiac arrhythmias in young patients with myotonic dystrophy type 1

被引：76

作者：

Bassez, G

Lazarus, A

Desguerre, I

Varin, J

Laforêt, P

Bécane, HM

Meune, C

Arne-Bes, MC

Ounnoughene, Z

Radvanyi, H

Eymard, B

Duboc, D

机构：

[1] Hop Cochin, Dept Cardiol, F-75679 Paris 14, France

[2] Grp Hosp Pitie Salpetriere, Myol Inst, F-75634 Paris, France

[3] Hop Henri Mondor, Dept Histol, F-94010 Creteil, France

[4] Hop Necker Enfants Malad, Child Neurol Unit, Dept Pediat, Paris, France

[5] Hop Rangueil, Dept Neurol, Toulouse, France

[6] Hop Ambroise Pare, Dept Mol Genet, Boulogne, France

来源：

NEUROLOGY | 2004年 / 63卷 / 10期

关键词：

D O I：

10.1212/01.WNL.0000144343.91136.CF

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cardiac tachyarrhythmias have rarely been studied in young patients with myotonic dystrophy type 1 (DM1). The authors observed major cardiac rhythm disturbances in 11 patients aged 10 to 18 years. Tachyarrhythmic events were more frequent than impulse conduction disorders. Wide variations in CTG expansion were observed among the population. Since physical exercise was a prominent arrhythmogenic factor, systematic exercise tests with EKG monitoring may be indicated in young patients with DM1.

引用

页码：1939 / 1941

页数：3

共 6 条

[1]

Duboc D, 2004, MYOTONIC DYSTROPHY: PRESENT MANAGEMENT, FUTURE THERAPY, P85

[2]

FORSBERG H, 1990, BRIT HEART J, V63, P119

[3]

Relationships among electrophysiological findings and clinical status, heart function, and extent of DNA mutation in myotonic dystrophy [J].