Measuring covert HIV replication during HAART: the abundance of 2-LTR circles is not a reliable marker

被引:24
作者
Bushman, F [1 ]
机构
[1] Salk Inst Biol Studies, Infect Dis Lab, La Jolla, CA 92037 USA
关键词
2-LTR circles; residual replication; HIV DNA; antiretroviral therapy;
D O I
10.1097/00002030-200303280-00014
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:749 / 750
页数:2
相关论文
共 13 条
[1]   Accumulation and intranuclear distribution of unintegrated human immunodeficiency virus type 1 DNA [J].
Bell, P ;
Montaner, LJ ;
Maul, GG .
JOURNAL OF VIROLOGY, 2001, 75 (16) :7683-7691
[2]   A quantitative assay for HIV DNA integration in vivo [J].
Butler, SL ;
Hansen, MST ;
Bushman, FD .
NATURE MEDICINE, 2001, 7 (05) :631-634
[3]  
BUTLER SL, 2002, J VIROL
[4]  
Coffin JM, 1997, RETROVIRUSES
[5]   Human immunodeficiency virus type 1-infected persons with residual disease and virus reservoirs on suppressive highly active antiretroviral therapy can be stratified into relevant virologic and immunologic subgroups [J].
Dornadula, G ;
Nunnari, G ;
Vanella, M ;
Roman, J ;
Babinchak, T ;
DeSimone, J ;
Stern, J ;
Braffman, M ;
Zhang, H ;
Pomerantz, RJ .
JOURNAL OF INFECTIOUS DISEASES, 2001, 183 (11) :1682-1687
[6]   CIRCULARIZATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 DNA INVITRO [J].
FARNET, CM ;
HASELTINE, WA .
JOURNAL OF VIROLOGY, 1991, 65 (12) :6942-6952
[7]   Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection [J].
Li, L ;
Olvera, JM ;
Yoder, KE ;
Mitchell, RS ;
Butler, SL ;
Lieber, M ;
Martin, SL ;
Bushman, FD .
EMBO JOURNAL, 2001, 20 (12) :3272-3281
[8]  
Livak F, 1996, MOL CELL BIOL, V16, P609
[9]   Identification of a human recent thymic emigrant phenotype [J].
McFarland, RD ;
Douek, DC ;
Koup, RA ;
Picker, LJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (08) :4215-4220
[10]   Residual HIV-1 disease in seminal cells of HIV-1-infected men on suppressive HAART: latency without on-going cellular infections [J].
Nunnari, G ;
Otero, M ;
Dornadula, G ;
Vanella, M ;
Zhang, H ;
Frank, I ;
Pomerantz, RJ .
AIDS, 2002, 16 (01) :39-45