Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil

被引:37
作者
de Goes Cavalcanti, Luciano Pamplona [1 ,2 ]
Branco Coelho, Ivo Castelo [3 ]
Lima Feitosa Vilar, Dina Cortez [4 ]
Silveira Holanda, Susana Gloria [4 ]
Farias da Escossia, Kiliana Nogueira [4 ]
Souza-Santos, Reinaldo [5 ]
机构
[1] Univ Fed Ceara, DSC, FM, Grad Program Med Sci, BR-60430140 Fortaleza, Ceara, Brazil
[2] Univ Fed Ceara, Dept Community Hlth, Fortaleza, Ceara, Brazil
[3] Univ Fed Ceara, Dept Pathol, Fortaleza, Ceara, Brazil
[4] Secretaria Saude Ceara, Fortaleza, Ceara, Brazil
[5] Natl Sch Publ Hlth, Rio De Janeiro, Brazil
关键词
Dengue hemorrhagic fever; Epidemiology; Risk factors;
D O I
10.1590/S0037-86822010000400003
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Introduction: The dengue hemorrhagic dengue (DHF) remains an important public health problem in Brazil. The objective of this study was to analyze the epidemiological characteristics of DHF cases during the 2003 epidemic in Ceara. Methods: Suspected DHF cases with onset of symptoms between January and December 2003 were investigated. Results: 37,964 classic dengue cases and 291 DHF cases were reported. Among the cases discarded, 75.5% were serologically positive but did not meet the criteria recommended by the World Health Organization (WHO). The DHF patients' median age was 30 years (2 - 88). Among the hemorrhagic manifestations, petechiae were the most (32.6%) frequent. Cases of gastrointestinal bleeding, ascites, pericardial pleural effusion, hepatomegaly, hypotension and shock showed higher risk of progression to death (p < 0.05). Conclusions: The introduction of a new serotype (DENV-3) in Ceara, which encountered a susceptible population and high vector density, may have been the primary agent responsible for the magnitude of the epidemic. Timely and appropriate medical care, along with an organized care structure are essential for reducing its lethality.
引用
收藏
页码:355 / 358
页数:4
相关论文
共 15 条
[1]  
Casali Clarisse Guimarães, 2004, Rev. Soc. Bras. Med. Trop., V37, P296, DOI 10.1590/S0037-86822004000400002
[2]  
CUNHA RV, 1988, MEM I O CRUZ, V93, P155
[3]  
Denis Cristiane K., 2003, Rev. Bras. Otorrinolaringol., V69, P644, DOI 10.1590/S0034-72992003000500009
[4]   Neurological manifestations of dengue: study of 41 cases [J].
Ferreira, MLB ;
Cavalcanti, CG ;
Coelho, CA ;
Mesquita, SD .
ARQUIVOS DE NEURO-PSIQUIATRIA, 2005, 63 (2B) :488-493
[5]   Dengue and dengue hemorrhagic fever [J].
Gubler, DJ .
CLINICAL MICROBIOLOGY REVIEWS, 1998, 11 (03) :480-+
[6]   Clinical and epidemiological aspects of the dengue epidemic in Recife, PE, 2002 [J].
Montenegro, D ;
Lacerda, HR ;
Lira, TM ;
de Oliveira, DSC ;
de Lima, AAF ;
Guimaraes, MJB ;
de Vasconcelos, PG .
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2006, 39 (01) :9-13
[7]  
Passos Maíla Naves Pereira, 2004, Rev. Soc. Bras. Med. Trop., V37, P293, DOI 10.1590/S0037-86822004000400001
[8]   Clinical-epidemiologic profile of Dengue suspicious cases in a district in the south zone of Teresina, Pl, Brazil [J].
Ribeiro, Polyana da Costa ;
de Sousa, Debora Costa ;
Evangelista de Araujo, Telma Maria .
REVISTA BRASILEIRA DE ENFERMAGEM, 2008, 61 (02) :227-232
[9]  
Rigau-Perez J G, 1997, Rev Panam Salud Publica, V1, P381
[10]   Epidemiology of dengue infection in Ribeirao Preto, SP, Brazil [J].
Rodrigues, EMS ;
Dal-Fabbro, AL ;
Salomao, R ;
Ferreira, IB ;
Rocco, IM ;
da Fonseca, BAL .
REVISTA DE SAUDE PUBLICA, 2002, 36 (02) :160-165