Acupuncture increases cell proliferation in dentate gyrus after transient global ischemia in gerbils

被引：101

作者：

Kim, EH

Kim, YJ

Lee, HJ

Huh, Y

Chung, JH

Seo, JC

Kang, JE

Lee, HJ

Yim, SV

Kim, CJ

机构：

[1] Semyung Univ, Coll Oriental Med, Dept Meridianol, Chungbuk 390711, South Korea

[2] Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea

[3] Kyung Hee Univ, Dept Acupuncture & Moxibust, Seoul 130701, South Korea

[4] Kyung Hee Univ, Grad Sch EW Med Sci, Dept Acunpunture & Meridianol, Seoul 449701, South Korea

[5] Kangwon Natl Univ, Coll Med, Dept Pharmacol, Chunchon 200701, South Korea

来源：

NEUROSCIENCE LETTERS | 2001年 / 297卷 / 01期

关键词：

ischemia; acupuncture; cell proliferation; dentate gyrus; gerbil;

D O I：

10.1016/S0304-3940(00)01656-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of acupuncture on cell proliferation in the dentate gyrus of gerbils after transient global ischemia were investigated in this study. Acupuncture was performed on Zusanli (ST36), which is a well known acupoint in animals and humans. In Oriental medicine, Zusanli has been commonly used for the enhancement of functional recovery in stroke patients. Through 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry, an increase in cell birth in the dentate gyrus of gerbils after ischemic injury was detected. Interestingly, acupunctural treatment in ischemic gerbils resulted in a significant increase in the number of BrdU-positive cells in the dentate gyrus. The present findings indicate that acupuncture may affect cell proliferation in the dentate gyrus of gerbils after ischemic injury. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：21 / 24

页数：4

共 20 条

[1] MIGRATION AND DISTRIBUTION OF 2 POPULATIONS OF HIPPOCAMPAL GRANULE CELL PRECURSORS DURING THE PERINATAL AND POSTNATAL PERIODS [J].