A formally zwitterionic ruthenium catalyst precursor for the transfer hydrogenation of ketones that does not feature an ancillary ligand N-H functionality

被引：94

作者：

Lundgren, Rylan J.

Rankin, Matthew A.

McDonald, Robert

Schatte, Gabriele

Stradiotto, Mark ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4J3, Canada

[2] Univ Alberta, Dept Chem, Xray Crystallography Lab, Edmonton, AB T6G 2M7, Canada

[3] Univ Saskatchewan, Saskatchewan Struct Sci Ctr, Saskatoon, SK S7N 5C9, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 25期

关键词：

homogeneous catalysis; ketones; ruthenium; transfer hydrogenation; zwitterions;

D O I：

10.1002/anie.200700345

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fast and furious: Even without the assistance of an N-H donor ligand, the Ra complex shown in the scheme is a remarkably active precatalyst for the transfer hydrogenation of ketones in basic iPrOH (R,R′ = alkyl oraryl), providing near-quantitative yields within minutes and exhibiting consistently high turnover frequencies (104 to 105 h-1) for a diverse range of substrates. (Chemical Equation Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4732 / 4735

页数：4

共 29 条

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