How I treat influenza in patients with hematologic malignancies

被引：81

作者：

Casper, Corey ^{[1
,2
,3
,4
,5
]}

Englund, Janet ^{[6
]}

Boeckh, Michael ^{[1
,3
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Inst, Seattle, WA 98109 USA

[2] Seattle Canc Care Alliance, Infect Control Program, Seattle, WA USA

[3] Univ Washington, Dept Med, Seattle, WA USA

[4] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

[5] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA

[6] Seattle Childrens Hosp, Res Inst, Seattle, WA USA

来源：

BLOOD | 2010年 / 115卷 / 07期

基金：

美国国家卫生研究院;

关键词：

RESPIRATORY VIRUS-INFECTIONS; CELL TRANSPLANT RECIPIENTS; CRITICALLY-ILL PATIENTS; STEM-CELL; A VIRUS; SEASONAL INFLUENZA; RIBAVIRIN THERAPY; ANTIVIRAL AGENTS; ORAL RIBAVIRIN; H1N1;

D O I：

10.1182/blood-2009-11-255455

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The 2009 H1N1 influenza pandemic has heightened the interest of clinicians for options in the prevention and management of influenza virus infection in immunocompromised patients. Even before the emergence of the novel 2009 H1N1 strain, influenza disease was a serious complication in patients with hematologic malignancies receiving chemotherapy or undergoing hematopoietic cell transplantation. Here we review the clinical manifestations of seasonal and 2009 H1N1 influenza and discuss current diagnosis, antiviral treatment, and prophylaxis options. We also summarize infection control and vaccination strategies for patients, family members, and caregivers. (Blood. 2010; 115: 1331-1342)

引用

页码：1331 / 1342

页数：12

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