Lenticular calcium, magnesium, and iron levels in diabetic rats and verapamil effect

被引：34

作者：

Cekic, O

Bardak, Y

机构：

[1] SSK Ankara Eye Hosp, Ankara, Turkey

[2] Suleyman Demirel Univ, Isparta, Turkey

来源：

OPHTHALMIC RESEARCH | 1998年 / 30卷 / 02期

关键词：

diabetes; cataract; calcium; magnesium; iron; verapamil;

D O I：

10.1159/000055462

中图分类号：

R77 [眼科学];

学科分类号：

100212 [眼科学];

摘要：

Lenticular calcium (Ca), magnesium (Mg), and iron (Fe) changes in diabetic rats and the effects of the Ca antagonist drug verapamil on this electrolyte imbalance were studied. Verapamil administration had no effect on the blood glucose values. Compared to the control group, a significant increase was observed in the lenticular Ca, Mg, and Fe content of the diabetic rats. Eight weeks of verapamil administration to the diabetic animals significantly reduced lenticular Ca, Mg, Fe values. Therefore it is suggested that verapamil might be a useful drug to prevent diabetic cataract formation.

引用

页码：107 / 112

页数：6

共 26 条

[1]

BENEFICIAL-EFFECTS OF VERAPAMIL IN DIABETIC CARDIOMYOPATHY [J].