Autoimmune thyroid diseases: Etiology, pathogenesis, and dermatologic manifestations

被引:89
作者
Ai, J [1 ]
Leonhardt, JM [1 ]
Heymann, WR [1 ]
机构
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Camden, NJ 08103 USA
关键词
D O I
10.1067/mjd.2003.257
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Autoimmune thyroid disease (AITD) including Graves' disease, Hashimoto's thyroiditis, and idiopathic hypothyroidism (atrophic Hashimoto's thyroiditis) is of vital concern to the dermatologist. This article reviews the cutaneous manifestations of Graves' disease and Hashimoto's thyroiditis. Recognition of dermatologic manifestations of AITD may alert practitioners to investigate for these disorders. The immune response involved in the pathogenesis of AITD is detailed. Current understanding of the role of genetic and environmental factors, antigens, and apoptosis are elaborated. The future holds exciting insight into the etiology, pathogenesis, and treatment of AITD.
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收藏
页码:641 / 659
页数:19
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