CLINICAL IMMUNOLOGY Culprits with evolutionary ties

被引:47
作者
Calfee, Carolyn S. [1 ,2 ,3 ]
Matthay, Michael A. [1 ,2 ,3 ]
机构
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Anesthesia, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA
关键词
D O I
10.1038/464041a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The cellular organelles we know as mitochondria are thought to have originated as symbiotic bacteria. Indeed, the two use common mechanisms to trigger innate immune responses to injury and infection, respectively.
引用
收藏
页码:41 / 42
页数:2
相关论文
共 9 条
[1]   Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion [J].
Cohen, Mitchell J. ;
Brohi, Karim ;
Calfee, Carolyn S. ;
Rahn, Pamela ;
Chesebro, Brian B. ;
Christiaans, Sarah C. ;
Carles, Michel ;
Howard, Marybeth ;
Pittet, Jean-Francois .
CRITICAL CARE, 2009, 13 (06) :R174
[2]  
Gray MW, 2001, GENOME BIOL, V2
[3]   Regulation of Adaptive Immunity by the Innate Immune System [J].
Iwasaki, Akiko ;
Medzhitov, Ruslan .
SCIENCE, 2010, 327 (5963) :291-295
[4]   Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury [J].
Looney, Mark R. ;
Nguyen, John X. ;
Hu, Yongmei ;
Van Ziffle, Jessica A. ;
Lowell, Clifford A. ;
Matthay, Michael A. .
JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (11) :3450-3461
[5]   Projections of global mortality and burden of disease from 2002 to 2030 [J].
Mathers, Colin D. ;
Loncar, Dejan .
PLOS MEDICINE, 2006, 3 (11) :2011-2030
[6]   Emerging paradigm: Toll-like receptor 4 - Sentinel for the detection of tissue damage [J].
Mollen, Kevin P. ;
Anand, Rahul J. ;
Tsung, Allan ;
Prince, Jose M. ;
Levy, Ryan M. ;
Billiar, Timothy R. .
SHOCK, 2006, 26 (05) :430-437
[7]   Postinjury multiple organ failure: A bimodal phenomenon [J].
Moore, FA ;
Sauaia, A ;
Moore, EE ;
Haenel, JB ;
Burch, JM ;
Lezotte, DC .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1996, 40 (04) :501-512
[8]   Medical progress - The acute respiratory distress syndrome. [J].
Ware, LB ;
Matthay, MA .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (18) :1334-1349
[9]   Circulating mitochondrial DAMPs cause inflammatory responses to injury [J].
Zhang, Qin ;
Raoof, Mustafa ;
Chen, Yu ;
Sumi, Yuka ;
Sursal, Tolga ;
Junger, Wolfgang ;
Brohi, Karim ;
Itagaki, Kiyoshi ;
Hauser, Carl J. .
NATURE, 2010, 464 (7285) :104-U115