Safety of solar phototherapy at the Dead Sea

被引:42
作者
Kushelevsky, AP
Harari, M
Kudish, AI
Hristakieva, E
Ingber, A
Shani, J
机构
[1] DMZ Rehabil Clin, IL-86930 Dead Sea, Israel
[2] Ben Gurion Univ Negev, Dept Nucl Engn, IL-84105 Beer Sheva, Israel
[3] Ben Gurion Univ Negev, Dept Chem Engn, IL-84105 Beer Sheva, Israel
[4] Hadassah Univ Hosp, Dept Dermatol, IL-91120 Jerusalem, Israel
[5] Hebrew Univ Jerusalem, Sch Pharm, Dept Pharmacol, IL-91120 Jerusalem, Israel
[6] Trakia Univ, Fac Med, Stara Zagora, Bulgaria
[7] Dead Sea Med Res Ctr, Neveh Zohar, Israel
[8] Hebrew Univ Jerusalem, David R Bloom Ctr Pharm, IL-91905 Jerusalem, Israel
关键词
D O I
10.1016/S0190-9622(98)70504-3
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Climatotherapy at the Dead Sea is effective for patients with psoriasis, atopic dermatitis, vitiligo, and other diseases. Although impressive improvement has been reported for patients with psoriasis, with a clearance rate of more than 80% after a 4-week stay, questions regarding the safety of this treatment have arisen. Objective and Methods: We compare the mean UVB radiation intensities absorbed by psoriatic patients undergoing a 4-week climatotherapy under supervision at the DMZ Rehabilitation Clinic of Ein-Bokek (The Dead Sea, Israel), with similar climatotherapy studies in Sweden and Switzerland, We also compare the climatotherapy radiation dosages with the UVB intensities absorbed by psoriatic patients in radiation cabins at seven university clinics. Results: According to our individually computerized DMZ protocol, a psoriasis patient with skin type IV is exposed during a 4-week climatotherapy to a mean 3.11 J/cm(2) (148 MED) of UVB, similar to that in Sweden and Switzerland. The range of the in-clinic annual phototherapy in the seven medical centers studied varied from 1.17 to 37.80 J/cm(2) (56 to 1800 MED). Conclusion: When all relevant factors are taken into account, the mean UVB exposure dose at the Dead Sea is one of the lowest reported for clearance of psoriatic plaques.
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收藏
页码:447 / 452
页数:6
相关论文
共 28 条
[1]  
Avrach W W, 1974, Ugeskr Laeger, V136, P2687
[2]   SEASONAL-VARIATIONS OF ERYTHEMA DOSE AT 2 ALPINE STATIONS IN DIFFERENT ALTITUDES [J].
BLUMTHALER, M ;
REHWALD, W ;
AMBACH, W .
ARCHIVES FOR METEOROLOGY GEOPHYSICS AND BIOCLIMATOLOGY SERIES B-THEORETICAL AND APPLIED CLIMATOLOGY, 1985, 35 (04) :389-397
[3]  
BRENNER W, 1983, Z HAUTKRANKHEITEN, V58, P1113
[4]  
CHRISTOPHERS E, 1994, HAUTARZT, V45, P119
[5]   UV-B DOSES RECEIVED DURING DIFFERENT OUTDOOR ACTIVITIES AND UV-B TREATMENT OF PSORIASIS [J].
DIFFEY, BL ;
LARKO, O ;
SWANBECK, G .
BRITISH JOURNAL OF DERMATOLOGY, 1982, 106 (01) :33-41
[6]  
DOSTROVSKY A., 1959, HAREFUAH, V57, P143
[7]   How much Dead Sea sun for psoriasis? [J].
EvenPaz, Z ;
Efron, D ;
Kipnis, V ;
Abels, DJ .
JOURNAL OF DERMATOLOGICAL TREATMENT, 1996, 7 (01) :17-19
[8]  
FITZPATRICK TB, 1991, DERMATOLOGY, P383
[9]   3II-NM UVB PHOTOTHERAPY - AN EFFECTIVE TREATMENT FOR PSORIASIS [J].
GREEN, C ;
FERGUSON, J ;
LAKSHMIPATHI, T ;
JOHNSON, BE .
BRITISH JOURNAL OF DERMATOLOGY, 1988, 119 (06) :691-696
[10]   Demographic evaluation of successful antipsoriatic climatotherapy at the Dead Sea (Israel) DMZ Clinic [J].
Harari, M ;
Shani, J .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1997, 36 (04) :304-308