Role of Extracellular DNA in Initial Bacterial Adhesion and Surface Aggregation

被引：243

作者：

Das, Theerthankar

Sharma, Prashant K.

Busscher, Henk J.

van der Mei, Henny C.

Krom, Bastiaan P. ^{[1
]}

机构：

[1] Univ Med Ctr Groningen, Dept Biomed Engn, Sector F, NL-9713 AV Groningen, Netherlands

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2010年 / 76卷 / 10期

关键词：

BIOFILM FORMATION; RELEASE; FORCES;

D O I：

10.1128/AEM.03119-09

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

引用

收藏

页码：3405 / 3408

页数：4

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