Riboswitch structures: Purine ligands replace tertiary contacts

被引：26

作者：

Lescoute, A ^{[1
]}

Westhof, E ^{[1
]}

机构：

[1] Univ Strasbourg 1, CNRS, UPR9002, Inst Biol Mol & Cellulaire, F-67084 Strasbourg, France

来源：

CHEMISTRY & BIOLOGY | 2005年 / 12卷 / 01期

关键词：

D O I：

10.1016/j.chembiol.2005.01.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two recent reports describe the fascinating crystal structures of the G-riboswitch complexed to three different purine ligands, hypoxanthine [1], guanine, and adenine [2].

引用

页码：10 / 13

页数：4

共 19 条

[1] Crystal structure of a group I intron splicing intermediate
Adams, PL
Stahley, MR
Gill, ML
Kosek, AB
Wang, JM
Strobel, SA
[J]. RNA, 2004, 10 (12) : 1867 - 1887
[2] Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine
Batey, RT
Gilbert, SD
Montange, RK
[J]. NATURE, 2004, 432 (7015) : 411 - 415
[3] Natural and engineered nucleic acids as tools to explore biology
Breaker, RR
[J]. NATURE, 2004, 432 (7019) : 838 - 845
[4] Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus:: Structure of the proteins and their interactions with 16 S RNA
Brodersen, DE
Clemons, WM
Carter, AP
Wimberly, BT
Ramakrishnan, V
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 316 (03) : 725 - 768
[5] Building programmable jigsaw puzzles with RNA
Chworos, A
Severcan, I
Koyfman, AY
Weinkam, P
Oroudjev, E
Hansma, HG
Jaeger, L
[J]. SCIENCE, 2004, 306 (5704) : 2068 - 2072
[6] Crystal structure of a conserved ribosomal protein-RNA complex
Conn, GL
Draper, DE
Lattman, EE
Gittis, AG
[J]. SCIENCE, 1999, 284 (5417) : 1171 - 1174
[7] A universal mode of helix packing in RNA
Doherty, EA
Batey, RT
Masquida, B
Doudna, JA
[J]. NATURE STRUCTURAL BIOLOGY, 2001, 8 (04) : 339 - 343
[8] Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
Kuglstatter, A
Oubridge, C
Nagai, K
[J]. NATURE STRUCTURAL BIOLOGY, 2002, 9 (10) : 740 - 744
[9] Geometric nomenclature and classification of RNA base pairs
Leontis, NB
Westhof, E
[J]. RNA, 2001, 7 (04) : 499 - 512
[10] Analysis of RNA motifs
Leontis, NB
Westhof, E
[J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2003, 13 (03) : 300 - 308

← 1 2 →