Context-dependent interactions and visual processing in V1

We examined the influence of stimulus context on the response of cells in primate V1 utilising both concentric and spatially discrete stimuli. The majority of cells (63/71) showed marked patch suppression, including non-oriented cells. This suppression was reduced or lost if there was an orientation discontinuity in the stimulus overlying the receptive field. Cross-oriented stimuli could exert strong facilitatory effects so that a cell's response to an optimally oriented stimulus over its receptive field was increased by the presence of an adjacent cross-oriented stimulus. This increase appeared to involve both disinhibition as well as a direct facilitation. The strength of the cross-orientation effects was such that for some cells it seemed appropriate to define a cross-oriented stimulus configuration as the 'optimal' stimulus. Effects following from orientation context could be strongly influenced by stimulus direction. Subcortical as well as cortical interactions may contribute to these observations. It is suggested that the properties of the network as a whole define the responses of individual cells and that the representation of discontinuities is an important component of network function in V1.