Diaphragm pacing during prolonged mechanical ventilation of the lungs could prevent from respiratory muscle fatigue

被引:18
作者
Pavlovic, D [1 ]
Wendt, M [1 ]
机构
[1] Ernst Moritz Arndt Univ Greifswald, Klin & Poliklin Anasthesie & Intensivmed, D-17487 Greifswald, Germany
关键词
D O I
10.1016/S0306-9877(02)00413-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Respiratory muscle fatigue after prolonged mechanical ventilation of the lungs is a common occurrence. This is probably due to disuse atrophy. The standard technique used to overcome this problem is to gradually wean the patient from the respirator over the course of several days or weeks. Hypothesis: based on experience with the rehabilitation of skeletal muscles during long-term immobilisation,of the extremities following trauma or surgery and on experience with diaphragm pacing in quadriplegics, intermittent electrical or magnetic stimulation of the diaphragm while the lungs are still being mechanically ventilated may be beneficial. The result of such stimulation would be to preserve the dysfunctioning diaphragm from atrophy. Consequences: dependence on the respirator, length of intubation time, risk of complications and length of stay in the ICU would be considerably reduced. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:398 / 403
页数:6
相关论文
共 69 条
[1]   ABDOMINAL AND THORACIC PRESSURES AT DIFFERENT LUNG VOLUMES [J].
AGOSTONI, E ;
RAHN, H .
JOURNAL OF APPLIED PHYSIOLOGY, 1960, 15 (06) :1087-1092
[2]   DIAPHRAGMATIC CONTRACTILITY ENHANCED BY AMINOPHYLLINE - ROLE OF EXTRACELLULAR CALCIUM [J].
AUBIER, M ;
MURCIANO, D ;
VIIRES, N ;
LECOCGUIC, Y ;
PARIENTE, R .
JOURNAL OF APPLIED PHYSIOLOGY, 1983, 54 (02) :460-464
[3]   AMINOPHYLLINE IMPROVES DIAPHRAGMATIC CONTRACTILITY [J].
AUBIER, M ;
DETROYER, A ;
SAMPSON, M ;
MACKLEM, PT ;
ROUSSOS, C .
NEW ENGLAND JOURNAL OF MEDICINE, 1981, 305 (05) :249-252
[4]   DETECTION OF DIAPHRAGMATIC FATIGUE IN MAN BY PHRENIC STIMULATION [J].
AUBIER, M ;
FARKAS, G ;
DETROYER, A ;
MOZES, R ;
ROUSSOS, C .
JOURNAL OF APPLIED PHYSIOLOGY, 1981, 50 (03) :538-544
[5]  
AUBIER M, 1984, J APPL PHYSIOL, V56, P922, DOI 10.1152/jappl.1984.56.4.922
[6]  
AUBIER M, 1983, AM REV RESPIR DIS, V127, P148
[7]   Prevention of human diaphragm atrophy with short periods of electrical stimulation [J].
Ayas, NT ;
McCool, FD ;
Gore, R ;
Lieberman, SL ;
Brown, R .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (06) :2018-2020
[8]  
Baldwin KM, 1996, MED SCI SPORT EXER, V28, pS101
[9]   Effects of different activity and inactivity paradigms on myosin heavy chain gene expression in striated muscle [J].
Baldwin, KM ;
Haddad, F .
JOURNAL OF APPLIED PHYSIOLOGY, 2001, 90 (01) :345-357
[10]  
BELMAN MJ, 1985, AM REV RESPIR DIS, V131, P226