Atherothrombosis, inflammation, and diabetes

被引:217
作者
Biondi-Zoccai, GGL [1 ]
Abbate, A [1 ]
Liuzzo, G [1 ]
Biasucci, LM [1 ]
机构
[1] Univ Cattolica Sacro Cuore, Inst Cardiol, I-00168 Rome, Italy
关键词
D O I
10.1016/S0735-1097(03)00088-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetes represents a major cause of cardiovascular morbidity and mortality in developed countries, and atherothrombosis accounts for most deaths among diabetics. Recent evidence has reliably shown the relevant etiopathogenetic role of inflammation in atherothrombotic disease. This review summarizes and discusses the possible synergistic effects of diabetes and inflammation in promoting atherothrombosis and its complications, as well as potential avenues for diagnostic, preventive, and therapeutic benefits in the modulation of inflammatory mechanisms in diabetic atherothrombotic disease. (C) 2003 by the American College of Cardiology Foundation.
引用
收藏
页码:1071 / 1077
页数:7
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