Lipid trafficking and sorting: how cholesterol is filling gaps

被引:42
作者
Hoekstra, D
van IJzendoorn, SCD
机构
[1] Univ Groningen, Dept Physiol Chem, NL-9713 AV Groningen, Netherlands
[2] Univ Calif San Francisco, Sch Med, Dept Anat, San Francisco, CA 94143 USA
关键词
D O I
10.1016/S0955-0674(00)00122-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Recent research has highlighted a role for cholesterol homeostasis in the regulation of trafficking and sorting of sphingolipids. This sorting may dictate the nature of the acyl chain species of phospholipids in the plasma membrane which, in turn, may govern the selective partitioning of these lipids into lateral domains. Recently, several proteins have been identified that play a role in the flow and sorting of all major lipid classes.
引用
收藏
页码:496 / 502
页数:7
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