Description and validation of a novel liquid metal-free device for venous congestion plethysmography

被引:36
作者
Christ, F [1 ]
Bauer, A
Brügger, D
Niklas, M
Gartside, IB
Gamble, J
机构
[1] Univ Munich, Clin Anaesthesiol, D-81377 Munich, Germany
[2] Univ London Imperial Coll Sci Technol & Med, Sch Med, Dept Physiol, London UB7, England
[3] Univ London Imperial Coll Sci Technol & Med, Sch Med, Dept Paediat, London UB7, England
关键词
fluid filtration capacity; isovolumetric venous pressure; noninvasive microcirculatory measurement;
D O I
10.1152/jappl.2000.89.4.1577
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
We present a newly developed electromechanical sensor with automated calibration for strain-gauge plethysmography (filtrass) and compare it to a conventional mercury-in-Silastic strain-gauge plethysmograph (MSG). Fluid filtration capacity (K-f) and isovolumetric venous pressure (Piv) of the limb were assessed noninvasively with both devices in 29 healthy volunteers. We found significantly higher K-f and Piv values with MSG [4.6 +/- 2.0 x 10(-3) ml.min(-1).mmHg(-1).100 ml tissue(-1) (K-f units; KfU) and 21.2 +/- 8.1 mmHg for Pvi], than with filtrass, giving values of 3.1 +/- 0.8 KfU and 15.1 +/- 7.1 mmHg. Because K-f and Piv are profoundly influenced by the calibration, we investigated the quality of the calibration signal and its impact on the obtained values. We could show that the reproducibility of repeated calibrations was higher with filtrass (58% lower mean I SD). The data were grouped according to the quality of calibration, and we found no significant difference in K-f and Piv between filtrass (3.0 +/- 0.7 KfU and 15.9 +/- 6.9 mmHg, respectively) and MSG with good calibration signal (3.3 +/- 0.8 KfU and 18.6 +/- 7.1 mmHg, respectively; no significant difference). However, we obtained significantly higher MSG values (5.6 +/- 2.0 KfU and 23.1 +/- 8.4 mmHg, respectively; P < 0.001) in the group with a bad calibration signal. We suggest that the filtrass sensor, which performs an automatic, standardized calibration procedure and shows a linear signal response to stretch, gives highly reproducible and reliable results and thus is more suitable for routine application.
引用
收藏
页码:1577 / 1583
页数:7
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