Prions and neurodegenerative diseases

被引：19

作者：

Hope, J ^{[1
]}

机构：

[1] Inst Anim Hlth, Compton RG20 7NN, Berks, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2000年 / 10卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00129-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The long-term, progressive decay of the central nervous system typifies prion diseases, a group of rare, transmissible maladies affecting humans, sheep, cattle and some other types of mammal. Little is known about the early molecular events in its pathogenesis but the diverse roles of PrP, the prion protein, in its destructive action have recently been re-emphasised.

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页码：568 / 574

页数：7

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