Determination of uremic toxins in biofluids: creatinine, creatine, uric acid and xanthines

被引：54

作者：

Kochansky, CJ ^{[1
]}

Strein, TG ^{[1
]}

机构：

[1] Bucknell Univ, Dept Chem, Lewisburg, PA 17847 USA

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2000年 / 747卷 / 1-2期

关键词：

reviews; creatinine; creatine; uric acid; xanthine;

D O I：

10.1016/S0378-4347(00)00119-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Rapid and accurate determination of small molecule metabolic end-products is vital for clinical diagnosis and study of many metabolic disorders and medical abnormalities. Chromatographic and electrophoretic techniques are attractive for clinical analyses because of the inherent ability to analyze multiple component biofluids and determine the analytes of interest with minimal interference from other species. This manuscript reviews recent (1990-present) developments in chromatography and electrophoresis methodology for the determination of creatinine, creatine, uric acid and xanthines in biofluids. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：217 / 227

页数：11

共 68 条

[1] SEPARATION OF XANTHINES AND URIC ACIDS BY CAPILLARY ZONE ELECTROPHORESIS AND MICELLAR ELECTROKINETIC CAPILLARY ELECTROPHORESIS [J].