Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study

被引：13

作者：

Warren-Gash, Charlotte ^{[1
,8
]}

Childs, Kate ^{[2
]}

Thornton, Alicia ^{[3
]}

Bhagani, Sanjay ^{[4
]}

Demma, Shirin ^{[5
,6
]}

Srivastava, Ankur ^{[5
]}

Leen, Clifford ^{[7
]}

Agarwal, Kosh ^{[2
]}

Rodger, Alison J. ^{[3
,4
]}

Sabin, Caroline A. ^{[3
]}

机构：

[1] UCL, Inst Hlth Informat, London, England

[2] Kings Coll Hosp London, Inst Liver Studies, London, England

[3] UCL, Res Dept Infect & Populat Hlth, London, England

[4] Royal Free London NHS Fdn Trust, Dept Infect Dis, London, England

[5] UCL, Inst Liver & Digest Hlth, Div Med, London, England

[6] Univ Catania, Dept Expt & Clin Med, Hepatol Unit, Catania, Italy

[7] Western Gen Hosp, Reg Infect Dis Unit, Edinburgh, Midlothian, Scotland

[8] Farr Inst Hlth Informat Res, 222 Euston Rd, London NW1 2DA, England

来源：

INFECTION | 2017年 / 45卷 / 02期

基金：

英国医学研究理事会; 美国国家卫生研究院;

关键词：

HIV; Hepatitis B; Hepatitis C; Co-infection; Cirrhosis; Liver transplantation; HUMAN-IMMUNODEFICIENCY-VIRUS; KIDNEY-TRANSPLANTATION; DISEASE; COINFECTION; RECIPIENTS; PROGRESSION; RIBAVIRIN; SURVIVAL; OUTCOMES;

D O I：

10.1007/s15010-016-0976-x

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

引用

页码：215 / 220

页数：6

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