Reversible folding-unfolding, aggregation protection, and multi-year stabilization, in high concentration protein solutions, using ionic liquids

被引：203

作者：

Byrne, Nolene ^{[1
]}

Wang, Li-Min ^{[1
]}

Belieres, Jean-Philippe ^{[1
]}

Angell, C. Austen ^{[1
]}

机构：

[1] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 26期

关键词：

D O I：

10.1039/b618943a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the reversible thermal unfolding/refolding, and long period stabilization against aggregation and hydrolysis, of > 200 mg ml(-1) solutions of lysozyme in ionic liquid-rich, ice-avoiding, solvents.

引用

页码：2714 / 2716

页数：3

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