Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS)

被引：826

作者：

Klomjai, Wanalee ^{[1
]}

Katz, Rose ^{[2
,3
]}

Lackmy-Vallee, Alexandra ^{[2
]}

机构：

[1] Mahidol Univ, Fac Phys Therapy, Nakonpathom 73170, Thailand

[2] Sorbonne Univ, UPMC Univ Paris 06, CNRS, INSERM,Lab Imagerie Biomed, F-75013 Paris, France

[3] Grp Hosp Pitie Salpetriere, AP HP, Serv Med Phys & Readaptat, Paris, France

来源：

ANNALS OF PHYSICAL AND REHABILITATION MEDICINE | 2015年 / 58卷 / 04期

关键词：

Transcranial magnetic stimulation (TMS); Human; Cortex;

D O I：

10.1016/j.rehab.2015.05.005

中图分类号：

R49 [康复医学];

学科分类号：

100232 [康复医学];

摘要：

Transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) are indirect and non-invasive methods used to induce excitability changes in the motor cortex via a wire coil generating a magnetic field that passes through the scalp. Today, TMS has become a key method to investigate brain functioning in humans. Moreover, because rTMS can lead to long-lasting after-effects in the brain, it is thought to be able to induce plasticity. This tool appears to be a potential therapy for neurological and psychiatric diseases. However, the physiological mechanisms underlying the effects induced by TMS and rTMS have not yet been clearly identified. The purpose of the present review is to summarize the main knowledge available for TMS and rTMS to allow for understanding their mode of action and to specify the different parameters that influence their effects. This review takes an inventory of the most-used rTMS paradigms in clinical research and exhibits the hypotheses commonly assumed to explain rTMS after-effects. (C) 2015 Elsevier Masson SAS. All rights reserved.

引用

页码：208 / 213

页数：6

共 42 条

[1]

Impulses in the pyramidal tract [J].