MAVID multiple alignment server

被引:38
作者
Bray, N [1 ]
Pachter, L [1 ]
机构
[1] Univ Calif Berkeley, Dept Math, Berkeley, CA 94720 USA
关键词
D O I
10.1093/nar/gkg623
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID web server allows biomedical researchers to quickly obtain multiple alignments for genomic sequences and to subsequently analyse the alignments for conserved regions. MAVID has been successfully used for the alignment of closely related species such as primates and also for the alignment of more distant organisms such as human and fugu. The server is fast, capable of aligning hundreds of kilobases in less than a minute. The multiple alignment is used to build a phylogenetic tree for the sequences, which is subsequently used as a basis for identifying conserved regions in the alignment. The server can be accessed at http://baboon.math.berkeley.edu/mavid/.
引用
收藏
页码:3525 / 3526
页数:2
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