Bioactive Hybrid Organogels Based on Miniemulsion Synthesis of Morphologically Complex Polymer/Surfactant/Calcium Phosphate Nanostructures

被引：14

作者：

Akkarachaneeyakorn, Khrongkhwan

Li, Mei

Harris, Joe

Davis, Sean A.

Mann, Stephen ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Ctr Organized Matter Chem, Bristol BS8 1TS, Avon, England

来源：

CHEMISTRY OF MATERIALS | 2014年 / 26卷 / 20期

关键词：

HYDROPHILIC BLOCK-COPOLYMERS; AMORPHOUS CALCIUM-PHOSPHATE; NANOPARTICLES; CRYSTALLIZATION; MINERALIZATION; MICROEMULSIONS;

D O I：

10.1021/cm5027305

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

Morphologically complex amorphous calcium phosphate nanostructures are synthesized within supersaturated water-in-oil miniemulsions stabilized by a mixture of a calcium bis(2-ethylhexyl)phosphate (Ca(DEHP)2) surfactant and poly(ethylene oxide)19-poly(propylene oxide)69-poly(ethylene oxide)19 (P123) triblock copolymer. Solvent evaporation at room temperature results in self-supporting viscous organogels comprising an interconnected network of calcium phosphate nanofilaments embedded within a continuous polymer/surfactant matrix. The P123/DEHP/calcium phosphate organogels are employed as a bioactive filler for the occlusion of exposed dentine tubules using a standard bovine tooth model. © 2014 American Chemical Society.

引用

页码：5965 / 5972

页数：8

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