Near-infrared spectroscopy applications in pharmaceutical analysis

被引：478

作者：

Luypaert, J. ^{[1
]}

Massart, D. L. ^{[1
]}

Heyden, Y. Vander ^{[1
]}

机构：

[1] Free Univ Brussels, Dept Analyt Chem & Pharmaceut Technol, Inst Pharmaceut, B-1090 Brussels, Belgium

来源：

TALANTA | 2007年 / 72卷 / 03期

关键词：

NIR; near-infrared spectroscopy; pharmaceutical; applications; review;

D O I：

10.1016/j.talanta.2006.12.023

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学]; 081704 [应用化学];

摘要：

Near-infrared (NIR) spectroscopy is a fast and non-destructive analytical technique that offers many advantages for a broad range of industrial applications. In this work, we reviewed recent developments in the pharmaceutical domain where it can be applied from raw material identification to final product release. The characteristics of NIR allow the technique to be implemented as a process analytical technology (PAT). Moreover, recent instrumental developments open the perspectives of numerous applications in the NIR imaging area. After "Introduction", according to their subject, the applications are discussed in the parts "Identification", "Water content", "Assay" and "Other applications". (C) 2007 Elsevier B.V. All rights reserved.

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收藏

页码：865 / 883

页数：19

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