Catastrophic antiphospholipid syndrome (CAPS): update from the 'CAPS Registry'

被引:66
作者
Cervera, R. [1 ]
机构
[1] Hosp Clin Barcelona, Serv Malalties Autoimmunes, Dept Autoimmune Dis, Barcelona 08036, Catalonia, Spain
关键词
anticardiolipin antibodies; antiphospholipid antibodies; antiphospholipid syndrome; catastrophic antiphospholipid syndrome; lupus anticoagulant; SERIES; CLASSIFICATION; CRITERIA;
D O I
10.1177/0961203309361353
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although less than 1% of patients with the antiphospholipid syndrome (APS) develop the catastrophic variant, its potentially lethal outcome emphasizes its importance in clinical medicine today. However, the rarity of this variant makes it extraordinarily difficult to study in any systematic way. In order to put together all of the published case reports as well as the new diagnosed cases from all over the world, an international registry of patients with catastrophic APS (CAPS Registry) was created in 2000 by the European Forum on Antiphospholipid Antibodies (see http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM). Currently, it documents the entire clinical, laboratory and therapeutic data of more than 300 patients whose data has been fully registered. Lupus (2010) 19, 412-418.
引用
收藏
页码:412 / 418
页数:7
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