p21WAF1/Cip1:: more than a break to the cell cycle?

被引:303
作者
Dotto, GP
机构
[1] Massachusetts Gen Hosp E, Charlestown, MA 02129 USA
[2] Harvard Univ, Sch Med, Cutaneous Biol Res Ctr, Charlestown, MA 02129 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | 2000年 / 1471卷 / 01期
关键词
cyclin/CDK; DNA synthesis; transcription; apoptosis; differentiation; stem cell renewal;
D O I
10.1016/S0304-419X(00)00019-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:M43 / M56
页数:14
相关论文
共 117 条
  • [1] The cell as a collection of protein machines: Preparing the next generation of molecular biologists
    Alberts, B
    [J]. CELL, 1998, 92 (03) : 291 - 294
  • [2] APPEL K, 1995, ONCOGENE, V11, P1971
  • [3] Complexity and the economy
    Arthur, WB
    [J]. SCIENCE, 1999, 284 (5411) : 107 - 109
  • [4] Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation
    Asada, M
    Yamada, T
    Ichijo, H
    Delia, D
    Miyazono, K
    Fukumuro, K
    Mizutani, S
    [J]. EMBO JOURNAL, 1999, 18 (05) : 1223 - 1234
  • [5] CALMODULIN AND CALMODULIN-BINDING PROTEINS IN THE NUCLEUS
    BACHS, O
    AGELL, N
    CARAFOLI, E
    [J]. CELL CALCIUM, 1994, 16 (04) : 289 - 296
  • [6] Functional analysis of a p21(WAF1,CIP1,SDI1) mutant (Arg(94)->trp) identified in a human breast carcinoma - Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases
    Balbin, M
    Hannon, GJ
    Pendas, AM
    Ferrando, AA
    Vizoso, F
    Fueyo, A
    LopezOtin, C
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (26) : 15782 - 15786
  • [7] The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development
    Balomenos, D
    Martín-Caballero, J
    García, MI
    Prieto, I
    Flores, JM
    Serrano, M
    Martínez, C
    [J]. NATURE MEDICINE, 2000, 6 (02) : 171 - 176
  • [8] Stress signals for apoptosis: ceramide and c-Jun kinase
    Basu, S
    Kolesnick, R
    [J]. ONCOGENE, 1998, 17 (25) : 3277 - 3285
  • [9] RADIATION-INDUCED CELL-CYCLE ARREST COMPROMISED BY P21 DEFICIENCY
    BRUGAROLAS, J
    CHANDRASEKARAN, C
    GORDON, JI
    BEACH, D
    JACKS, T
    HANNON, GJ
    [J]. NATURE, 1995, 377 (6549) : 552 - 557
  • [10] Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after γ-irradiation
    Brugarolas, J
    Moberg, K
    Boyd, SD
    Taya, Y
    Jacks, T
    Lees, JA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (03) : 1002 - 1007