The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya I. Development of infrastructure and description of study site

被引:73
作者
Phillips-Howard, PA
Nahlen, BL
Alaii, JA
ter Kuile, FO
Gimnig, JE
Terlouw, DJ
Kachur, SP
Hightower, AW
Lal, AA
Schoute, E
Oloo, AJ
Hawley, WA
机构
[1] Ctr Dis Control & Prevent, Div Parasit Dis, Natl Ctr Infect Dis, Atlanta, GA 30341 USA
[2] Kenya Govt Med Res Ctr, Ctr Vector Biol & Control Res, Kisumu, Kenya
[3] Univ Amsterdam, Acad Med Ctr, Dept Infect Dis Trop Med & AIDS, NL-1105 AZ Amsterdam, Netherlands
关键词
D O I
10.4269/ajtmh.2003.68.3
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Randomized controlled trials in sub-Saharan Africa have shown that permethrin-treated bed nets and curtains reduce all-cause child mortality by 15-33% in areas with low or high but seasonal malaria transmission. This report describes the study site for a community-based, group-randomized, controlled trial in an area of high and year-round malaria transmission in western Kenya. We outline the development of the human and physical infrastructure required to conduct this trial and discuss some of the difficulties encountered and lessons learned in conducting it.
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页码:3 / 9
页数:7
相关论文
共 27 条
[1]   Factors affecting use of permethrin-treated bed nets during a randomized controlled trial in western Kenya [J].
Alaii, JA ;
Hawley, WA ;
Kolczak, MS ;
ter Kuile, FO ;
Gimnig, JE ;
Vulule, JM ;
Odhacha, A ;
Oloo, AJ ;
Nahlen, BL ;
Phillips-Howard, PA .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2003, 68 (04) :137-141
[2]  
ALAII JA, 1997, THESIS LONDON BANK U
[3]   EFFECTIVENESS OF PERMETHRIN-IMPREGNATED BED NETS AND CURTAINS FOR MALARIA CONTROL IN A HOLOENDEMIC AREA OF WESTERN KENYA [J].
BEACH, RF ;
RUEBUSH, TK ;
SEXTON, JD ;
BRIGHT, PL ;
HIGHTOWER, AW ;
BREMAN, JG ;
MOUNT, DL ;
OLOO, AJ .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1993, 49 (03) :290-300
[4]   PLASMODIUM-FALCIPARUM INCIDENCE RELATIVE TO ENTOMOLOGIC INOCULATION RATES AT A SITE PROPOSED FOR TESTING MALARIA VACCINES IN WESTERN KENYA [J].
BEIER, JC ;
OSTER, CN ;
ONYANGO, FK ;
BALES, JD ;
SHERWOOD, JA ;
PERKINS, PV ;
CHUMO, DK ;
KOECH, DV ;
WHITMIRE, RE ;
ROBERTS, CR ;
DIGGS, CL ;
HOFFMAN, SL .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1994, 50 (05) :529-536
[5]  
Binka FN, 1996, TROP MED INT HEALTH, V1, P147
[6]   Longitudinal cohort study of the epidemiology of malaria infections in an area of intense malaria transmission II. Descriptive epidemiology of malaria infection and disease among children [J].
Bloland, PB ;
Boriga, DA ;
Ruebush, TK ;
McCormick, JB ;
Roberts, JM ;
Oloo, AJ ;
Hawley, W ;
Lal, A ;
Nahlen, B ;
Campbell, CC .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1999, 60 (04) :641-648
[7]   BEYOND CHLOROQUINE - IMPLICATIONS OF DRUG-RESISTANCE FOR EVALUATING MALARIA THERAPY EFFICACY AND TREATMENT POLICY IN AFRICA [J].
BLOLAND, PB ;
LACKRITZ, EM ;
KAZEMBE, PN ;
WERE, JBO ;
STEKETEE, R ;
CAMPBELL, CC .
JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (04) :932-937
[8]   Longitudinal cohort study of the epidemiology of malaria infections in an area of intense malaria transmission I. Description of study site, general methodology, and study population [J].
Bloland, PB ;
Ruebush, TK ;
McCormick, JB ;
Ayisi, J ;
Boriga, DA ;
Oloo, AJ ;
Beach, R ;
Hawley, W ;
Lal, A ;
Nahlen, B ;
Udhayakumar, V ;
Campbell, CC .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1999, 60 (04) :635-640
[9]  
Cohen David, 1989, Siaya: the historical anthropology of an African landscape
[10]   MORTALITY AND MORBIDITY FROM MALARIA IN GAMBIAN CHILDREN AFTER INTRODUCTION OF AN IMPREGNATED BEDNET PROGRAM [J].
DALESSANDRO, U ;
OLALEYE, BO ;
MCGUIRE, W ;
LANGEROCK, P ;
BENNETT, S ;
AIKINS, MK ;
THOMSON, MC ;
CHAM, MK ;
CHAM, BA ;
GREENWOOD, BM .
LANCET, 1995, 345 (8948) :479-483