The effects of superoxide dismutase on H2O2 formation

被引：176

作者：

Liochev, Stefan I. ^{[1
]}

Fridovich, Irwin ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA

来源：

FREE RADICAL BIOLOGY AND MEDICINE | 2007年 / 42卷 / 10期

关键词：

superoxide; superoxide dismutase; hydrogen peroxide; nitric oxide; overproduction; models; free radicals;

D O I：

10.1016/j.freeradbiomed.2007.02.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Numerous reports of the effects of overproduction of SODs have been explained on the basis of increased H2O2 production by the catalyzed dismutation of O-2(-). In this review we consider the effects of increasing [SOD] on H2O2 formation and question this explanation. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：1465 / 1469

页数：5

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