Six new constituents from the roots of Erythrina variegata

被引:25
作者
Tanaka, H [1 ]
Hirata, M
Etoh, H
Sako, M
Sato, M
Murata, J
Murata, H
Darnaedi, D
Fukai, T
机构
[1] Meijo Univ, Fac Pharm, Tempaku Ku, Nagoya, Aichi 4688503, Japan
[2] Shizuoka Univ, Fac Agr, Shizuoka 4228529, Japan
[3] Gifu Pharmaceut Univ, Gifu 5028585, Japan
[4] Asahi Univ, Sch Dent, Dept Oral Pathol, Gifu 5010296, Japan
[5] Univ Tokyo, Grad Sch Sci, Bot Gardens, Bunkyo Ku, Tokyo 1120001, Japan
[6] Setsunan Univ, Fac Pharmaceut Sci, Hirakata, Osaka 5730101, Japan
[7] Bot Gardens, Indonesian Inst Sci, Bogor 16122, Indonesia
[8] Toho Univ, Sch Pharmaceut Sci, Chiba 2748510, Japan
关键词
D O I
10.1002/cbdv.200490082
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three new isoflavonoids, eryvarins M-O (1-3), two new 2-arylbenzofurans, eryvarins P and Q (4 and 5), and a new 3-aryl-2,3-dihydrobenzofuran, eryvarin R (6), together with three known compounds, were isolated from the roots of Erythrina variegata. The structures of these compounds were established by spectroscopic analysis. Eryvarin R (6) is an unusual 3-aryl-2,3-dihydrobenzofuran derivative with a formyl (CHO) group. Eryvarin Q (5) showed potent antibacterial activity against methicillin-resistant Staphylococcus aureus.
引用
收藏
页码:1101 / 1108
页数:8
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