The vascular endothelial growth factor family and its receptors

被引：51

作者：

Parikh, AA

Ellis, LM

机构：

[1] Temple Univ, Sch Med, Dept Surg Oncol, Philadelphia, PA 19140 USA

[2] Univ Texas, MD Anderson Canc Ctr, Dept Surg Oncol & Canc Biol, Houston, TX 77230 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2004年 / 18卷 / 05期

关键词：

D O I：

10.1016/j.hoc.2004.06.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This article focuses on describing the biology of vascular endothelial growth factor (VEGF) and its receptors as well as the regulation of their expression. A thorough understanding of the VEGF system is paramount in optimizing antiangiogenic therapies as a component of antineoplastic regimens.

引用

收藏

页码：951 / +

页数：22

相关论文

共 178 条

[1] Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells [J].

Abedi, H ;

Zachary, I .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (24) :15442-15451

[2]

Achen MG, 2001, J PATHOL, V193, P147, DOI 10.1002/1096-9896(2000)9999:9999<::AID-PATH757>3.0.CO

[3]

2-G

[4] Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4) [J].

Achen, MG ;

Jeltsch, M ;

Kukk, E ;

Mäkinen, T ;

Vitali, A ;

Wilks, AF ;

Alitalo, K ;

Stacker, SA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (02) :548-553

[5] Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells [J].

Akagi, M ;

Kawaguchi, M ;

Liu, W ;

McCarty, MF ;

Takeda, A ;

Fan, F ;

Stoeltzing, O ;

Parikh, AA ;

Jung, YD ;

Bucana, CD ;

Mansfield, PF ;

Hicklin, DJ ;

Ellis, LM .

BRITISH JOURNAL OF CANCER, 2003, 88 (05) :796-802

[6]

Akagi Y, 1998, CANCER RES, V58, P4008

[7] VASCULAR ENDOTHELIAL GROWTH-FACTOR ACTS AS A SURVIVAL FACTOR FOR NEWLY FORMED RETINAL-VESSELS AND HAS IMPLICATIONS FOR RETINOPATHY OF PREMATURITY [J].

ALON, T ;

HEMO, I ;

ITIN, A ;

PEER, J ;

STONE, J ;

KESHET, E .

NATURE MEDICINE, 1995, 1 (10) :1024-1028

[8]

Aoki T, 2002, ONCOL REP, V9, P761

[9] Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1 [J].

Banks, RE ;

Forbes, MA ;

Searles, J ;

Pappin, D ;

Canas, B ;

Rahman, D ;

Kaufmann, S ;

Walters, CE ;

Jackson, A ;

Eves, P ;

Linton, G ;

Keen, J ;

Walker, JJ ;

Selby, PJ .

MOLECULAR HUMAN REPRODUCTION, 1998, 4 (04) :377-386

[10] Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1 [J].

Barleon, B ;

Sozzani, S ;

Zhou, D ;

Weich, HA ;

Mantovani, A ;

Marme, D .

BLOOD, 1996, 87 (08) :3336-3343

← 1 2 3 4 5 6 7 8 9 10 →