Hypoglycemic activity of Nymphaea stellata leaves ethanolic extract in alloxan induced diabetic rats

被引:34
作者
Dhanabal, S. P. [1 ]
Raja, M. K. Mohan Maruga
Ramanathan, M.
Suresh, B.
机构
[1] JSS Coll Pharm, Dept Pharmacognosy & Pharmacol, Ootacamund, Tamil Nadu, India
[2] PSG Coll Pharm, Dept Pharmacol, Coimbatore, Tamil Nadu, India
关键词
Nymphaea stellata; hypoglycemic activity; alloxan; biochemical parameters;
D O I
10.1016/j.fitote.2007.02.009
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
The ethanolic extract of leaves of Nymphaea stellata given by oral route to diabetic rats at dose of 100 and 200 mg/kg/day for seven days reduced significantly by 31.6 and 42.6% the plasma glucose level increased by intraperitoneal injection of 120 mg/day of alloxan. Moreover, the treatment significantly affected the plasma level of cholesterol and triglyceride. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:288 / 291
页数:4
相关论文
共 23 条
[1]
ADDAE-MENSAH I, 1989, Fitoterapia, V60, P359
[2]
ORAL HYPOGLYCEMIC PLANTS IN WEST-AFRICA [J].
BEVER, BO .
JOURNAL OF ETHNOPHARMACOLOGY, 1980, 2 (02) :119-127
[3]
Chude M. A., 2001, Indian Journal of Pharmacology, V33, P215
[4]
Ghosh Sumana, 2001, Indian Journal of Experimental Biology, V39, P748
[5]
Hawk P.B., 1954, Practical Physiological Chemistry
[6]
HUFF MW, 1977, ATHEROSCLEROSIS, V28, P187, DOI 10.1016/0021-9150(77)90156-3
[7]
*IND MIN HLTH FAM, 1996, IND PHARM, P80
[8]
Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats [J].
Kameswararao, B ;
Kesavulu, MM ;
Apparao, C .
FITOTERAPIA, 2003, 74 (1-2) :7-13
[9]
KEDAR P, 1982, INDIAN J EXP BIOL, V20, P232
[10]
KIRTIKAR KR, 1999, INDIAN MED PLANTS, V1, P114