The anaemia of infection

被引：68

作者：

Means, RT

机构：

[1] Med Univ S Carolina, Div Hematol Oncol, Charleston, SC 29425 USA

[2] Ralph H Johnson VA Med Ctr, Hematol Oncol Sect, Charleston, SC USA

来源：

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY | 2000年 / 13卷 / 02期

关键词：

anaemia; infection; cytokines; ferrokinetics; erythropoietin; iron; host defence;

D O I：

10.1053/beha.1999.0065

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Anaemia is a common finding in infected individuals, and in many cases is an indicator of disease activity and/or duration. The term 'anaemia of infection' refers to a specific syndrome related to the more broadly defined 'anaemia of chronic disease', in this syndrome, cytokines produced as part of the host response to infection induce anaemia by well-defined pathophysiological mechanisms. In this chapter, the diagnosis, significance, pathophysiology and treatment of the anaemia of infection will be reviewed. Other mechanisms which can produce anaemia in infected individuals will also be reviewed.

引用

页码：151 / 162

页数：12

共 99 条

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REGULATION OF TRANSFERRIN RECEPTORS BY IRON IN HUMAN ERYTHROBLASTS [J].