A journey from neocortex to hippocampus

被引：7

作者：

Bliss, TVP ^{[1
]}

机构：

[1] Natl Inst Med Res, Div Neurophysiol, London NW7 1AA, England

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 2003年 / 358卷 / 1432期

关键词：

neocortex to hippocampus; long-term potentiation; synaptic plasticity; Hebb; learning; memory;

D O I：

10.1098/rstb.2002.1227

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

In the mid-1960s, it was generally agreed that the engram, the neural trace of previously experienced events, must be encoded by Hebb-like neurons in which synaptic efficacy could be modified by activity. Here, I describe my attempts as a PhD student at McGill University, Montreal, to find rules governing cortical plasticity in the neocortex, and having failed, why the hippocampus seemed to offer a far better prospect.

引用

页码：621 / 623

页数：3

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