Cytochrome P-450 under pressure - More evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension

被引:16
作者
Fleming, I [1 ]
机构
[1] Univ Frankfurt, Inst Kardiovaskulare Physiol, Vasc Signalling Grp, D-60590 Frankfurt, Germany
关键词
editorials; cytochrome P-450 enzyme system; hypertension; kidney; vasoconstriction;
D O I
10.1161/01.CIR.0000152695.11867.D8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:5 / 7
页数:3
相关论文
共 20 条
[1]   Characterization of the CYNA11 gene, a second CYP4A gene in humans [J].
Bellamine, A ;
Wang, YR ;
Waterman, MR ;
Dawson, EP ;
Brown, NJ ;
Capdevila, JH .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2003, 409 (01) :221-227
[2]   Inhibition of cytochrome P4502C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease [J].
Fichtlscherer, S ;
Dimmeler, S ;
Breuer, S ;
Busse, R ;
Zeiher, AM ;
Fleming, I .
CIRCULATION, 2004, 109 (02) :178-183
[3]   Endothelium-derived hyperpolarizing factor synthase (cytochrome P4502C9) is a functionally significant source of reactive oxygen species in coronary arteries [J].
Fleming, I ;
Michaelis, UR ;
Bredenkötter, D ;
Fisslthaler, B ;
Dehghani, F ;
Brandes, RP ;
Busse, R .
CIRCULATION RESEARCH, 2001, 88 (01) :44-51
[4]   Cytochrome P450 enzymes in vascular homeostasis [J].
Fleming, I .
CIRCULATION RESEARCH, 2001, 89 (09) :753-762
[5]   Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension [J].
Gainer, JV ;
Bellamine, A ;
Dawson, EP ;
Womble, KE ;
Grant, SW ;
Wang, YR ;
Cupples, LA ;
Guo, CY ;
Demissie, S ;
O'Donnell, CJ ;
Brown, NJ ;
Waterman, MR ;
Capdevila, JH .
CIRCULATION, 2005, 111 (01) :63-69
[6]   Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension [J].
Holla, VR ;
Adas, F ;
Imig, JD ;
Zhao, XY ;
Price, E ;
Olsen, N ;
Kovacs, WJ ;
Magnuson, MA ;
Keeney, DS ;
Breyer, MD ;
Falck, JR ;
Waterman, MR ;
Capdevila, JH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (09) :5211-5216
[7]   Localization of cytochrome P-450 4A isoforms along the rat nephron [J].
Ito, O ;
Alonso-Galicia, M ;
Hopp, KA ;
Roman, RJ .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 1998, 274 (02) :F395-F404
[8]   20-HETE and circulating insulin in essential hypertension with obesity [J].
Laffer, CL ;
Laniado-Schwartzman, M ;
Nasjletti, A ;
Elijovich, F .
HYPERTENSION, 2004, 43 (02) :388-392
[9]   20-HETE and furosemide-induced natriuresis in salt-sensitive essential hypertension [J].
Laffer, CL ;
Laniado-Schwartzman, M ;
Wang, MH ;
Nasjletti, A ;
Elijovich, F .
HYPERTENSION, 2003, 41 (03) :703-708
[10]   Differential regulation of natriuresis by 20-hydroxyeicosatetraenoic acid in human salt-sensitive versus salt-resistant hypertension [J].
Laffer, CL ;
Laniado-Schwartzmann, M ;
Wang, MH ;
Nasjletti, A ;
Elijovich, F .
CIRCULATION, 2003, 107 (04) :574-578