Reduction of migraine attacks during the use of warfarin

Two recent reports on reduction of migraine attacks during treatment with vitamin K antagonists have caught my attention.(1,2) Being a migraine sufferer myself. with considerable improvement of my headache during the use of warfarin, I became interested in the subject. Recently, a young man sought my advice for migraine attacks which had worsened after the withdrawal of warfarin. The previous reports on migraine and warfarin involved elderly patients.(1,2) I report now on these two patients in their 30s, one of them being myself (case 1), who have experienced reduction of migraine attacks during the use of warfarin.