Gaucher disease: assessment of skeletal involvement and therapeutic responses to enzyme replacement

被引：51

作者：

Hermann, G

Pastores, GM

Abdelwahab, IF

Lorberboym, AM

机构：

[1] Mt Sinai Med Ctr, Dept Radiol, New York, NY 10029 USA

[2] Mt Sinai Med Ctr, Dept Human Genet, New York, NY 10029 USA

[3] Mt Sinai Med Ctr, Dept Pediat, New York, NY 10029 USA

[4] Mt Sinai Med Ctr, Dept Nucl Med, New York, NY 10029 USA

来源：

SKELETAL RADIOLOGY | 1997年 / 26卷 / 12期

关键词：

Gaucher disease type 1; imaging CT; MRI; Gaucher disease; skeletal changes;

D O I：

10.1007/s002560050313

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The clinical, pathological and radiological manifestations of type 1 Gaucher disease and the role of imaging techniques such as CT, MRI and sulfur-colloid scintigraphy in the management of these patients is discussed. MRI appears to be the most valuable imaging technique for evaluating bone marrow involvement and detecting disease activity. MRI is also useful in assessing therapeutic responses to enzyme replacement therapy.

引用

页码：687 / 696

页数：10

共 55 条

[1] EFFECT OF SPLENECTOMY ON DESTRUCTIVE BONE CHANGES IN CHILDREN WITH CHRONIC (TYPE-I) GAUCHER DISEASE [J].