Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development

被引：62

作者：

Hidalgo-Sánchez, M

Alvarado-Mallart, RM

Alvarez, IS

机构：

[1] Univ Extremadura, Fac Ciencias, Dept Biol Celular, E-06071 Badajoz, Spain

[2] Hop La Pitie Salpetriere, INSERM, U106, F-75651 Paris 13, France

来源：

MECHANISMS OF DEVELOPMENT | 2000年 / 95卷 / 1-2期

关键词：

Pax2; Otx2; Gbx2; Fgf8; chick embryo; otic placode; acoustic-vestibular ganglion; gene expression pattern;

D O I：

10.1016/S0925-4773(00)00332-4

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The inner ear is a suitable system to study the mechanisms involved in the specification of different functional domains during morphogenesis. Using single and double in situ hybridization (ISH) we show that three transcription factors (Otx2, Gbx2 and Pax2) and a member of the fibroblast growth factor family (Fgf8) could participate in the compartmentalization of the otic vesicle and in the formation of the acoustic-vestibular ganglion. (C) 2000 Elsevier Science ireland Ltd. All rights reserved.

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页码：225 / 229

页数：5

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